Aptamer DNA Polymerase is an aptamer-mediated, “warm-start” enzyme developed to remove the need for a high-temperature hot start PCR stage, ideal for rapid cycling or where high temperatures need to be avoided.
Aptamer DNA Polymerase is an aptamer-based, “warm-start” enzyme and the first choice for fast PCR reactions. The exceptional quality and purity of the enzyme ensure the highest performance, suitable for standard and fast PCR cycling in both endpoint and real-time assays. It ensures high product yields with low background and without primer–dimer formation or non-specific priming. The aptamer binds to Taq DNA Polymerase and inhibits the enzyme activity at temperatures below 45°C. This ensures full hot-start functionality. The enzyme is released during standard PCR cycling conditions so there is no need for separate heating or denaturation steps, allowing fast PCR reactions.